Spectrophotometric method for estimation of bisoprolol fumarate in tablets.
نویسندگان
چکیده
UNLABELLED Bisoprolol fumarate is prescribed for the treatment of hypertension and angina pectoris. AIM The purpose of this study was to develop a simple, sensitive, accurate, and reproducible method for estimation of bisoprolol fumarate in tablets. MATERIAL AND METHODS The proposed method was based on a yellow colored complex formed with tropaeolin 00, extractable in dichloromethane with maximum absorbance at 412 nm. The method was validated statistically. RESULTS The linearity domain was observed in the concentration of 5-30 microg/ml. The recovery studies confirmed the accuracy of the proposed method. CONCLUSIONS The proposed method can be applied for the routine analysis of bisoprolol from formulations.
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ورودعنوان ژورنال:
- Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi
دوره 118 2 شماره
صفحات -
تاریخ انتشار 2014